Anthony Chalmers, MD, University of Glasgow, Glasgow, UK, describes the challenges of treating glioblastoma. Presently, effective therapies may enable patients to live 3 to 5 years longer, though this result is only useful in younger patients or those with O6-methylguanine-DNA-methyltransferase (MGMT)-methylated tumors. In the elderly and in MGMT-unmethylated cases, present therapies do not improve OS beyond 1 year. More research is needed in this area particularly. This interview took place at the British Thoracic Oncology Group (BTOG) Annual Conference 2023 in Belfast, UK.
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