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SABCS 2025 | Selecting patients with breast cancer for neratinib after neoadjuvant HER2 therapy

Rupert Bartsch • 23 Dec 2025
SABCS 2025
Breast Cancer Neratinib Trastuzumab emtansine

Rupert Bartsch, MD, Medical University of Vienna, Vienna, Austria, highlights the potential candidates with breast cancer for neratinib treatment. The integration of trastuzumab emtansine (T-DM1) in the neoadjuvant setting may impact the use of neratinib, particularly in patients with hormone receptor-positive, HER2-positive disease, and neratinib may still be beneficial in patients with residual tumor load after T-DM1 treatment. This interview took place at the San Antonio Breast Cancer Symposium (SABCS) 2025 Meeting in San Antonio, TX.

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