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ASCO 2024 | Safety and anti-tumor activity of BAY 2927088 in patients with HER2-mutant NSCLC

Nicolas Girard, MD, PhD, Institut Curie, Paris, France, shares findings from a trial on BAY 2927088, a tyrosine kinase inhibitor, for HER2-mutant NSCLC. Among 34 patients treated, a majority showed objective responses and a promising median progression-free survival was also reported. BAY 2927088 demonstrated a favorable safety profile, with common adverse events being mild diarrhea and rash. The study supports further development of BAY 2927088 in patients with HER2-mutant NSCLC. This interview took place during the 2024 American Society of Clinical Oncology (ASCO) Meeting in Chicago, IL.

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Disclosures

Employment – AstraZeneca (I)
Consulting or Advisory Role – Abbvie; AMGEN; AstraZeneca; BeiGene; Bristol-Myers Squibb; Daiichi Sankyo/Astra Zeneca; Gilead Sciences; Ipsen; Janssen; LEO Pharma; Lilly; MSD; Novartis; Pfizer; Roche; Sanofi; Takeda
Research Funding – AstraZeneca (Inst); BMS (Inst); MSDavenir (Inst); Roche (Inst)
Travel, Accommodations, Expenses – Janssen Oncology; Janssen Oncology; Roche