Wungki Park, MD, MS, Memorial Sloan Kettering Cancer Center, New York, NY, provides an overview of a Phase II trial (NCT03816163) evaluating zolbetuximab with gemcitabine and nab-paclitaxel (GN) for claudin 18.2-positive metastatic pancreatic cancer. Primary endpoints include confirming the recommended Phase II dose and comparing safety and efficacy of the combination therapy versus GN alone. Secondary outcomes include progression-free survival, response rates, and quality of life metrics. This interview took place at the European Society for Medical Oncology (ESMO) 2024 Congress in Barcelona, Spain.
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