ESMO 2024 | MYTHOS: trastuzumab deruxtecan in HER2+ salivary gland cancer
Ichiro Kinoshita, MD, PhD, Hokkaido University Hospital, Sapporo, Japan, discusses findings from the Phase II MYTHOS trial (jRCT2011210017), evaluating trastuzumab deruxtecan (T-DXd) in HER2-positive recurrent/metastatic salivary gland cancer. The study showed an encouraging objective response rate and common grade 3/4 adverse events included neutropenia and lymphopenia, with manageable interstitial lung disease. These promising results support T-DXd as a potential therapeutic option for this rare cancer. This interview took place at the European Society for Medical Oncology (ESMO) 2024 Congress in Barcelona, Spain.
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