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WCLC 2025 | The importance of identifying high-risk lung cancer patients for screening

Mattias Johansson, International Agency for Research on Cancer, Lyon, France, emphasizes the importance of risk stratification in identifying individuals with at least one or several risk factors for lung cancer, rather than screening the general population, including never-smokers. Biomarkers are needed to help identify high-risk individuals, as the number of never-smokers with sufficiently high risk to warrant screening is expected to be very low. This interview took place at 2025 World Conference on Lung Cancer (WCLC) in Barcelona, Spain.

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Transcript

Well, I think the most important point is really that most people who never smoked have really very low risk of lung cancer. And there’s really no reason to go and screen just everyone who never smoked. So the risk stratification aspect of this to identify those with at least one or perhaps several risk factors for lung cancer is really crucial. But I think we also need perhaps biomarkers that can help identify those high-risk people...

Well, I think the most important point is really that most people who never smoked have really very low risk of lung cancer. And there’s really no reason to go and screen just everyone who never smoked. So the risk stratification aspect of this to identify those with at least one or perhaps several risk factors for lung cancer is really crucial. But I think we also need perhaps biomarkers that can help identify those high-risk people. If we look at the risk factors that we currently have a good understanding of, there would be very, very few never smokers who have a sufficiently high risk to be screened for lung cancer.

This transcript is AI-generated. While we strive for accuracy, please verify this copy with the video.

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