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WCLC 2025 | Addition of cardiovascular disease screening in lung cancer screening
Rozemarijn Vliegenthart, MD, PhD, University Medical Center Groningen, Groningen, Netherlands, discusses combining lung cancer screening with coronary calcium screening on the same chest CT scan, as both are strongly related to cardiovascular risk and can be detected with a single scan. This approach could increase the cost-effectiveness of screening programs by identifying individuals at risk for both lung and cardiovascular diseases. This interview took place at 2025 World Conference on Lung Cancer (WCLC) in Barcelona, Spain.
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Transcript
I think there is a great opportunity to combine lung cancer screening with screening for coronary calcium because it’s on the same scan. We know from studies that the amount of coronary calcium, even on the chest CT scan, even at low dose, has a strong relation to the risk of cardiovascular events. And we know from screen trials like NLST and Nelson that as many people die due to cardiovascular disease as due to lung cancer in the screening cohort...
I think there is a great opportunity to combine lung cancer screening with screening for coronary calcium because it’s on the same scan. We know from studies that the amount of coronary calcium, even on the chest CT scan, even at low dose, has a strong relation to the risk of cardiovascular events. And we know from screen trials like NLST and Nelson that as many people die due to cardiovascular disease as due to lung cancer in the screening cohort. So we could catch those two diseases with one scan. And we also know that when you have a lot of coronary calcium, you should have your cardiovascular risk factors reviewed and then treated if needed. And that, I think, will increase the cost-effectiveness of the screening program.
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