Yinghong Wang, MD, PhD, from The University of Texas MD Anderson Cancer Center, discusses the challenges of immune checkpoint inhibitor-induced gastrointestinal (GI) toxicities and the need for effective, minimally immunosuppressive treatments. Immune checkpoint inhibitors have proven effective against cancer but can lead to significant GI toxicities. Current treatments involve potent immunosuppression, but refractory cases remain. Fecal transplantation is explored as a potential alternative. Dr. Wang’s study aims to utilize fecal transplant as a frontline treatment, aiming to minimize immunosuppression exposure while addressing colitis effectively. This discussion took place at the American Society of Clinical Oncology (ASCO) 2023 Annual Congress in Chicago, IL.
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