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SABCS 2020 | Tailoring medicine in breast cancer

Erika Hamilton, MD, Sarah Cannon Research Institute, Nashville, TN, discusses the importance of tailoring medicine in the treatment of early breast cancer, and cites the results of the KATHERINE trial (NCT01772472), evaluating trastuzumab emtansine versus transtuzumab as adjuvant therapy in patients with HER2-positive breast cancer who have residual tumor in the breast or axillary lymph nodes following preoperative therapy, where biology was used to inform treatment decisions. This interview was recorded via an online conference call with The Video Journal of Oncology (VJOncology).

Disclosures

Dr. Hamilton reports consulting fees paid to institution only (no personal fees) from: Pfizer, Genentech/Roche, Lilly, Puma Biotechnology, Daiichi Sankyo, Mersana Therapeutics, Boehringer Ingelheim, AstraZeneca, Novartis, Silverback Therapeutics, Black Diamond and NanoString

Dr. Hamilton reports and research/clinical trial support paid to institution only (no personal fees) from: Seattle Genetics, Puma, AstraZeneca, Hutchinson MediPharma, OncoMed, MedImmune, StemCentrx, Genentech/Roche, Curis, Verastem, Zymeworks, Syndax, Lycera, Rgenix, Novartis, Mersana, Millenium, TapImmune, Lilly, BerGenBio, Medivation, Pfizer, Tesaro, Boehringer Ingelheim, Eisai, H3 Biomedicine, Radius Health, Acerta, Takeda, Macrogenics, Abbvie, Immunomedics, FujiFilm, Effector, Merus, Nucana, Regeneron, Leap Therapeutics, Taiho Pharmaceutical, EMD Serono, Daiichi Sankyo, ArQule, Syros, Clovis, Cytomx, InventisBio, Deciphera, Unum Therapeutics, Sermonix Pharmaceuticals, Sutro, Aravive, Zenith Epigenetics, Arvinas, Torque, Harpoon, Fochon, Black Diamond, Orinove, Molecular Templates, Silverback Therapeutics, Compugen, G1Therapeutics, Karyopharm Therapeutics and Torque Therapeutics.

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