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TTLC 2026 | Current PD-(L)1 and VEGF combinations and future bispecifics in NSCLC

Natalie Vokes, MD, The University of Texas MD Anderson Cancer Center, Houston, TX, discusses the history and development of PD-(L)1 and VEGF combinations, as well as bispecifics, in the treatment of non-small cell lung cancer (NSCLC). Previous trials combining PD-1 inhibitors with VEGF inhibitors have shown mixed results, which often showed improvement in progression-free survival but not overall survival, and newer bispecifics may offer a more promising approach. This interview took place at International Association for the Study of Lung Cancer (IASLC) 2026 Targeted Therapies of Lung Cancer Meeting (TTLC) in Huntington Beach, CA.

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