Melissa Johnson, MD, Sarah Cannon Research Institute, Nashville, TN, discusses IL-2 immunomodulatory agents for advanced non-small cell lung cancer (NSCLC). Although IL-2-targeting agents have demonstrated substantial promise in treating NSCLC, they have also been associated with significant toxicity. Dr Johnson reviews the immunobiology of the IL-2 receptor to explain the resulting associated toxicity and suggests methods to reduce toxicity and enhancing efficacy. This interview was recorded via an online conference call with The Video Journal of Oncology (VJOncology).
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