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ESMO 2024 | Clinical challenges in treating clear cell sarcoma

Javier Martin-Broto, MD, PhD, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain, gives an overview of clear cell sarcoma, an ultra-rare, highly aggressive subtype of sarcoma that predominantly affects young adults. Known for its rapid metastatic spread, particularly to lymph nodes, clear cell sarcoma is generally resistant to chemotherapy and antiangiogenics. With a median overall survival often less than one year and limited response to MET inhibitors, it represents a significant unmet clinical need due to the scarcity of effective treatments. This interview took place at the European Society for Medical Oncology (ESMO) 2024 Congress in Barcelona, Spain.

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