Yeah, interestingly, barriers have been examined in clinical trials, but clinical trial entry is slightly different from the barriers that people face in real-world screening. Even when they’re not randomised trials, it’s different. But we do know that practical barriers, the cost of travelling, the time that it takes, other things like comorbidities can be barriers to patients, that the psychological risk of actually gaining some knowledge that they didn’t want to know before and the fear of that knowledge is also a barrier...
Yeah, interestingly, barriers have been examined in clinical trials, but clinical trial entry is slightly different from the barriers that people face in real-world screening. Even when they’re not randomised trials, it’s different. But we do know that practical barriers, the cost of travelling, the time that it takes, other things like comorbidities can be barriers to patients, that the psychological risk of actually gaining some knowledge that they didn’t want to know before and the fear of that knowledge is also a barrier. So we know that we can try to mitigate these, but as I said, the lung screening uptake trial didn’t really show any important benefit from trying to mitigate those fears. And when you look at the practical programme, we do see some remarkably different uptake rates of offers. And one of the things that I think is very important in the British programme is the fact that the programmes are run by local people from the local population who speak the local dialect and are generally very passionate about getting patients into the programme because they’ve probably experienced lung cancer in their own lives. And this is probably the key to getting over those barriers, having people on the ground that really believe in the intervention of lung cancer screening, getting involved. And we’ve seen some amazing results in the UK as a result of that.
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