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ASCO 2026 | Multiomic spatial analysis of tumor microenvironment during NE transformation in EGFR-mutant LUAC
Triparna Sen, PhD, of The Ohio State University, discusses a multiomic spatial analysis of the tumor microenvironment during neuroendocrine (NE) transformation in EGFR-mutant lung adenocarcinoma (LUAC). Dr Sen highlights findings showing broad immune suppression during transformation, alongside the emergence of immunosuppressive macrophage populations that may represent future therapeutic targets. This interview took place during the 2026 American Society of Clinical Oncology (ASCO) Meeting in Chicago, IL.
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